ZOFRAN 8 mg 10 film-coated tablets in Box (ondansetron)


What is Zofran n what is it used for?
Zofran belongs to a group of medicines called antiemetics. Zofran is used to prevent nausea and vomiting that may occur:
• during cancer treatment (chemotherapy or radiation)
• after surgery under general anesthesia.
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To prevent nausea and vomiting after cancer treatment


On the day of treatment:
The usual dose in adults is 8 mg taken one to two hours before treatment and twelve hours later.

In the next few days:
The usual adult dose is 8 mg twice daily for up to five days.

Children> 6 months and adolescents:
Your doctor will decide on the right dose of Zofran for your child. The usual dose is up to 8 mg daily (up to 4 mg twice daily) for up to five days.

To prevent nausea and vomiting after surgery

The usual adult dose is 16 mg one hour before surgery.

Children> 1 month old and adolescents
Zofran tablets are not recommended. Zofran can be given as an intravenous injection.

How to take Zofran?
Swallow the tablets whole with a little water.
Tell your doctor or nurse if you feel sick.

If you forget to take Zofran
Take the missed dose as soon as possible and then take the next dose at the usual time. Do not take a double dose to make up for a forgotten dose.
If you are not sure what to do, ask your doctor or pharmacist.

If you take more Zofran than you should
If you accidentally take more Zofran tablets, it is not likely to cause you problems, but if you are worried or not feeling well:
Ask your doctor or pharmacist for advice.
Do not stop taking Zofran without consulting your doctor
Take Zofran for as long as your doctor has told you. Do not stop taking Zofran unless your doctor advises you to do so.

4. Possible side effects
Like all medicines, Zofran can cause side effects, although not everybody gets them.

Severe allergic reactions: These are rare in people taking Zofran. Signs include:
• raised and itchy rash (hives)
• swelling, sometimes on the face or mouth (angioedema), causing difficulty breathing
• collapse.

Contact your doctor immediately if you get these symptoms. Stop taking Zofran.

Very common side effects:
They may affect more than 1 in 10 patients:
• headache.

Common side effects:
They can affect up to 1 in 10 patients:
• Feeling warm or flushing

Uncommon side effects:
They can affect up to 1 in 100 patients:
• seizures
• involuntary muscle movements or spasms
• irregular heart rhythm
• chest pain
• low blood pressure
• hiccups.

Uncommon side effects that can occur through blood tests:
• Enhancement of substances (enzymes) produced by the liver.

Rare side effects
They can affect up to 1 in 1,000 patients:
• severe allergic reactions
• heart rhythm disturbance (which sometimes leads to sudden loss of consciousness)
• dizziness
• temporarily blurred or impaired vision.

Very rare side effects
They can affect up to 1 in 10,000 patients:
• extensive rash with blisters and skin exfoliation from much of the body surface (toxin epidermal necrolysis)
• temporary blindness.
If any of the side effects gets serious or troublesome, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.

5. How to store Zofran?
Keep out of the reach and sight of children.

Do not use Zofran after the expiry date which is stated on the pack.
Store below 30 ° C.
Do not dispose of medicines in sewage or household waste. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.

6. Contents of the pack and other information

What does Zofran contain?
The active substance is ondansetron. Each tablet contains 4 mg or 8 mg of ondansetron as hydrochloride dihydrate.
The other ingredients are: lactose, anhydrous, microcrystalline cellulose, pregelatinized corn starch, magnesium stearate, methylhydroxypropylcellulose, dangerous yellow M-1-8429 (contains titanium dioxide (E171) and iron oxide (E172)),

What does Zofran look like and contents of the pack?
The tablets containing 4 mg ondansetron are yellow in color, elliptical, biconvex “GXET3” on one side and smooth on the other.





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