MORPHINE SOPHARMA 20 mg / ml solution for injection
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each 1 ml ampoule contains the active substance morphine hydrochloride 20 mg.
For the nullification of severe pain of different origin (myocardial infarction, terminal malignancy, severe trauma, surgery), non-narcotic analgesics.
4.2 Posology and method of administration
The product is administered intravenously, intramuscularly, subcutaneously. A local irritation and pain reaction may occur with subcutaneous administration.
Intravenous administration: 5-15 mg / 70 kg diluted in 5 ml water for injection, slowly intravenously over 5 minutes.
Continuous intravenous infusion: 0.1-1 mg / ml in isotonic sodium chloride solution. The infusion rate is individually determined and can range from 0.8 to 80 mg / h.
Intramuscular and subcutaneous: 10 mg every 4 hours, with the dose ranging from 5 mg to 20 mg.
Adult patients over 65 years; half of the recommended dose for adults, as this group of patients develops more often respiratory depression and / or respiratory arrest following morphine administration.
Discontinuation of morphine therapy should be gradual, as abrupt reduction of dose or interruption of treatment may lead to withdrawal syndrome.
MARKETING AUTHORIZATION NUMBER (S)
20010308- 10 mg / ml
20010309- 20 mg / ml