Kreon 25 000 gastro resistant capsules, hard 25000 (300 mg) x20


• Creon contains a mixture of enzymes called “pancreatin”.
• Pancreatin helps digest food. The enzymes are from the pancreatic glands of the pigs.
• Creon contains small pellets that slowly release pancreatin into the intestines (gastro-resistant pellets called microspheres).
What is Creon used for?
Creon is used in children and adults with “pancreatic extracrine insufficiency.” It is a condition in which the body does not produce enough enzymes to break down food.
Cystic fibrosis – a rare hereditary disease;
Obstructed pancreatic or bile ducts (pancreatic duct or common bile duct)
Acute Pancreatic Inflammation (Pancreatitis) You may take Creon when
start eating again
Chronic inflammation of the pancreas (pancreatitis)
Pancreatic cancer
Partial or complete surgical removal of the pancreas (partial or total iancreatectomy)
Partial or complete surgical removal of the stomach (partial or complete gastrectomy) Gastrointestinal bypass
Schwahman-Diamond syndrome, a very rare genetic disorder.
How does Creon work?
The enzymes in Creon act to digest the food as it passes through the intestine. You must take Creon during or after a meal. This will allow the enzymes to mix

• If you are allergic (hypersensitive) to the active substance (s) or any of the other ingredients of Creon.
If you are not sure about something, mile, ask our doctor!
Take special care with Krson
In patients with high-dose pancreatin cystic fibrosis, a rare condition called “fibrotic colonopathy” has been reported. with the bowels narrowing. However, this is not known to have occurred during studies in patients taking Creon. However, if you have cystic fibrosis, take more than 10,000 units of lipase / kg per day and have unusual abdominal symptoms or changes in these symptoms, tell your doctor!
Further information on pencreatic enzymes
The pancreatic glands from which Creon and other pancreatic enzymes are produced are from pigs used for food. These animals can carry viruses. Several steps are being taken in the production of Creon to reduce the risk of virus spread, incl. destruction and testing for specific viruses. The risk of infections caused by these or other unknown or new viruses cannot be completely ruled out. However, there have been no reported cases of infection in patients.
Fertility, pregnancy and lactation
Please tell your doctor before you take this medicine if you are pregnant or planning to become pregnant! Your doctor will decide if you can take Creon and at what dose.
Creon may be taken during lactation. Taking other medicines
Please. tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription:
Driving and using machines
Creon is not likely to affect the ability to drive and use machines.

Always take Creon exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
What dose to take
• Your dose is measured in “lipase units.” Lipase is one of the enzymes in pancreatin. Different Creon dosages contain different amounts of lipase.
• Always follow your doctor’s advice on what dose of Creon to take.
• Your doctor will tailor your dose to your needs. It depends on:
– Your illness
– Your weight
– Your diet
– How much fat is there in your feces.
• If you still have fatty stools, other stomach or intestinal problems (gastrointestinal symptoms), tell your doctor as your dose may need to be adjusted.
Cystic fibrosis
• The usual starting dose for children under 4 years of age is 1000 lipase units per kilogram per meal.
• The usual starting dose for children over 4 years of age, adolescents and adults, is 500 lipase units per kilogram per meal.
Other pancreatic problems
• The usual feeding dose is between 25,000 and 80,000 lipase units.
• The usual dose to eat between meals is half that of the main meal.
When to take Creon
Always take Creon during or after eating or eating. This will allow the enzymes to completely mix with the food, digest it and pass it through the gut.
How to take Creon
• Swallow capsules whole.
• Do not break or chew the capsules.
• If you find it difficult to swallow the capsules, open them carefully and add the pellets to a small amount of soft acidic foods or mix them with acidic liquids. An acidic food, for example, may be apple sauce or yogurt. For example, acidic liquids are apple, orange or pineapple juice.
• Swallow the mixture immediately without breaking or chewing and drink some water or juice.
• Mixing with non-acidic foods and liquids, breaking or chewing on pellets can cause




Each Creon 25000 Ph.Eur.XJ capsule contains 300 mg of pancreatin (pancreatic powder) corresponding to: amylase 18 000 Ph. Eur. Units; lipase 25,000 Ph. Eur. Units; protease 1000 Ph. Eur. Units
The other ingredients are: macrogol 4000, hypromellose phthalate, dimethicone 1000, cetyl alcohol, triethyl citrate, gelatin, iron oxide (E 172), titanium dioxide (E 171), sodium lauryl sulfate


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