Activelle® 1 mg/0,5 mg 28 film-coated tablets (Estradiol/norethisterone acetate)


What Activive® contains
The active substances are estradiol 1 mg (such as estradiol hemihydrate) and norethisterone acetate 0.5 mg.
The other ingredients are lactose monohydrate, corn starch, copovidone, talc and magnesium stearate.
The shell contains: hypromellose, triacetin and talc.

What Activive® looks like and contents of the pack
The film-coated tablets are white, round, 6 mm in diameter. The tablets are engraved with “NOVO 288 * ‘on one side and the Novo Nordisk logo (Apis bull) on the other.

1 x 28 film-coated tablets in calendar pack

What is Activevel® and what it is used for

Activive® is a continuous combination hormone replacement therapy (HRT). It contains two types of female hormones, estrogen and progestogen. Activive® is used in postmenopausal women whose menstruation stopped more than 1 year ago.

Activive® is used for:
Relieving symptoms that occur after menopause
During menopause, the amount of estrogen formed in a woman’s body decreases. This can cause symptoms such as hot face, neck and breasts (“hot flushes”) – Activivel® relieves these symptoms after menopause. You will only be prescribed Activivel® if your symptoms severely complicate your daily routine.

Osteoporosis prevention
After menopause, some women may develop bone thinning (osteoporosis). You should discuss with your doctor all treatment options.
If you are at increased risk for osteoporosis fractures and if other medicines are not suitable for you, you can use Activive® to prevent osteoporosis after menopause.

Activive® is prescribed to women whose uterus has not been removed and whose menstruation stopped more than 1 year ago.
There is limited experience in the treatment of women older than 65 years with Activive®.



BY Novo Nordisk


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